Fmri Functional Connectivity Applied to Adolescent Neurodevelopment

Posted: 1 Apr 2015

See all articles by Monique Ernst

Monique Ernst

Government of the United States of America - National Institute of Mental Health

Salvatore Torrisi

Department of Economics, Management and Statistics; Bocconi University

Nicholas Balderston

Government of the United States of America - National Institute of Mental Health

Christian Grillon

Government of the United States of America - National Institute of Mental Health

Elizabeth Hale

Government of the United States of America - National Institute of Mental Health

Date Written: March 2015

Abstract

The exponential rise in the number of functional brain connectivity studies, particularly those examining intrinsic functional connectivity (iFC) at rest, and the promises of this work for unraveling the ontogeny of functional neural systems motivate this review. Shortly before this explosion in functional connectivity research, developmental neuroscientists had proposed theories based on neural systems models to explain behavioral changes, particularly in adolescence. The current review presents recent advances in imaging in brain connectivity research, which provides a unique tool for the study of neural systems. Understanding the potential of neuroimaging for refining neurodevelopmental models of brain function requires a description of various functional connectivity approaches. In this review, we describe task-based and resting-state functional magnetic resonance imaging (fMRI) analytic strategies, but we focus on iFC findings from resting-state data to describe general developmental trajectories of brain network organization. Finally, we use the example of drug addiction to frame a discussion of psychopathology that emerges in adolescence.

Suggested Citation

Ernst, Monique and Torrisi, Salvatore and Balderston, Nicholas and Grillon, Christian and Hale, Elizabeth, Fmri Functional Connectivity Applied to Adolescent Neurodevelopment (March 2015). Annual Review of Clinical Psychology, Vol. 11, pp. 361-377, 2015, Available at SSRN: https://ssrn.com/abstract=2588403 or http://dx.doi.org/10.1146/annurev-clinpsy-032814-112753

Monique Ernst (Contact Author)

Government of the United States of America - National Institute of Mental Health ( email )

6001 Executive Boulevard, Rm. 7117, MSC 9629
Bethesda, MA 20892
United States

Salvatore Torrisi

Department of Economics, Management and Statistics ( email )

Piazza dell'Ateneo Nuovo, 1
Milano, Milan 20126
Italy

HOME PAGE: http://https://www.unimib.it/salvatore-torrisi

Bocconi University ( email )

Via Sarfatti, 25
Milan, MI 20136
Italy

Nicholas Balderston

Government of the United States of America - National Institute of Mental Health ( email )

6001 Executive Boulevard, Rm. 7117, MSC 9629
Bethesda, MA 20892
United States

Christian Grillon

Government of the United States of America - National Institute of Mental Health ( email )

6001 Executive Boulevard, Rm. 7117, MSC 9629
Bethesda, MA 20892
United States

Elizabeth Hale

Government of the United States of America - National Institute of Mental Health ( email )

6001 Executive Boulevard, Rm. 7117, MSC 9629
Bethesda, MA 20892
United States

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